Epitalon
Also known as · Epithalon · Epithalamin tetrapeptide
Overview
A synthetic tetrapeptide derived from research on pineal extracts. Investigated in Russian gerontology literature for telomerase expression and circadian regulation in preclinical models.
Research profile · for clinicians
Based on research: investigated in gerontology and circadian biology. Cell-culture and rodent work has looked at telomerase (TERT) expression and restoration of age-related declines in melatonin rhythm — the basis for its frequent appearance in longevity and pineal-function research.
Mechanism of action
Reported in cell-culture work to upregulate telomerase reverse transcriptase (TERT) expression and to influence melatonin secretion patterns in aged rodent models.
Research record
- [01]Cell-culture telomerase activity (Khavinson et al., 2003).
- [02]Long-term rodent cohort studies on lifespan endpoints.
Selected references
Peptide promotes overcoming of the division limit
Bull. Exp. Biol. Med., 2003