All categories5-AMINO-1MQEPITALONFOXO4-DRIHUMANINMOTS-CNAD-PLUSSS-31
Category
Longevity & Mitochondrial
Mitochondrial-derived peptides and senescence-modulating compounds investigated in aging biology.
Longevity & Mitochondrial
5-Amino-1MQ
5-amino-1-methylquinolinium
- MW
- 159.2 g/mol
- Half-life
- Not formally characterised in humans
- Class
- Small-molecule NNMT inhibitor (non-peptide)
Longevity & Mitochondrial
Epitalon
Epithalon · Epithalamin tetrapeptide
- MW
- 390.35 g/mol
- Half-life
- Short (minutes)
- Class
- Synthetic tetrapeptide
Longevity & Mitochondrial
FOXO4-DRI
FOXO4 D-retro-inverso peptide
- MW
- ≈ 5100 g/mol
- Half-life
- Extended by D-amino-acid protease resistance
- Class
- Senolytic peptide (p53-FOXO4 interaction disruptor)
Longevity & Mitochondrial
Humanin
HN · HNG (potent analogue)
- MW
- 2687.2 g/mol
- Half-life
- Short in plasma; analogues extended
- Class
- Mitochondrial-derived peptide
Longevity & Mitochondrial
MOTS-c
- MW
- 2174.6 g/mol
- Half-life
- Short (preclinical)
- Class
- Mitochondrial-derived peptide (MDP)
Longevity & Mitochondrial
NAD+
Nicotinamide Adenine Dinucleotide
- MW
- 663.4 g/mol
- Half-life
- Tissue-specific; intracellular pool turns over within hours
- Class
- Pyridine dinucleotide coenzyme (not a peptide)
Longevity & Mitochondrial
SS-31
Elamipretide · MTP-131 · Bendavia
- MW
- 639.8 g/mol
- Half-life
- ≈ 2–4 h (SC)
- Class
- Mitochondria-targeted tetrapeptide