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Healing & Tissue Repair

GHK-Cu

Also known as · Copper Tripeptide-1

Overview

A naturally occurring copper-binding tripeptide. Studied in dermal repair, hair-follicle biology, and gene-expression profiling research with measurable effects on extracellular-matrix turnover.

Research profile · for clinicians

Based on research: a copper-binding tripeptide studied for skin, hair-follicle, and connective-tissue remodeling. Gene-expression profiling in fibroblasts shows shifts in extracellular-matrix synthesis, antioxidant defense, and wound-repair pathways — a common reference point in dermal repair and cosmetic-science literature.

Mechanism of action

Modulates expression of genes involved in extracellular matrix remodeling, antioxidant defense (SOD), and angiogenesis; delivers copper ions for cofactor-dependent enzymes.

Research record

  • [01]Genome-wide expression profiling in fibroblast cultures.
  • [02]Dermal repair and anti-fibrotic preclinical studies.

Selected references

  • GHK peptide as a natural modulator of multiple cellular pathways

    BioMed Res. Int., 2015