Tesa/Ipa 2X Blend (12mg / 3mg)
Also known as · Tesamorelin + Ipamorelin 12/3
Overview
A 4:1 (12 mg / 3 mg) GHRH-weighted blend studied for amplified GHRH signaling with a lower-dose secretagogue co-stimulus.
Research profile · for clinicians
Based on research: a GHRH-weighted version of the tesamorelin + ipamorelin combination for studies emphasizing baseline GHRH-receptor tone with a smaller secretagogue co-stimulus.
Mechanism of action
Higher tesamorelin content drives GHRH-receptor activation; the lower ipamorelin component provides adjunct GHSR-1a tone for synchronized pulse amplification.
Research record
- [01]Derived from the same mechanistic body of work as the 5/5 ratio.
- [02]No published clinical trials of the fixed-ratio blend.
Selected references
Tesamorelin pharmacology review
Drugs, 2011