3X Blend (Tesa / Ipa / MGF)
Also known as · Tesamorelin + Ipamorelin + MGF 5/2.5/0.5
Overview
A 5 mg / 2.5 mg / 0.5 mg triple blend pairing GHRH and ghrelin-receptor activation with mechano-growth factor (IGF-1Ec splice variant), studied in preclinical work for combined GH-axis stimulation and satellite-cell activation in skeletal muscle.
Research profile · for clinicians
Based on research: extends the tesamorelin + ipamorelin GH-axis stimulus with mechano-growth factor, an IGF-1 splice variant studied for activation of quiescent muscle satellite cells and myoblast proliferation in skeletal-muscle repair models.
Mechanism of action
Tesamorelin + ipamorelin amplify endogenous GH/IGF-1; MGF (IGF-1Ec) is reported to activate quiescent muscle satellite cells and promote myoblast proliferation independent of mature IGF-1.
Research record
- [01]Preclinical satellite-cell activation studies with MGF (Goldspink et al.).
- [02]No published clinical trials of the fixed-ratio triple blend.
Selected references
Mechano-growth factor and muscle repair
J. Musculoskelet. Neuronal Interact., 2005