Cerebrolysin
Also known as · FPF-1070
Overview
A standardised peptide preparation derived from porcine brain protein, used in several countries for stroke recovery, traumatic brain injury, and vascular dementia.
Research profile · for clinicians
Based on research: one of the most-trialled neurorestorative preparations, with Cochrane reviews of stroke and dementia data. Effect sizes are debated and trial quality varies by region.
Mechanism of action
The peptide fraction exerts neurotrophic-factor-like effects — supporting neuronal survival, dendritic sprouting, and synaptogenesis — while limiting excitotoxic and apoptotic signalling after injury.
Research record
- [01]CARS trial: improved motor recovery after ischaemic stroke.
- [02]Cochrane reviews report inconsistent evidence quality across indications.
Selected references
Cerebrolysin and recovery after stroke (CARS): a randomized controlled trial
Stroke, 2016
Research deep dive
Every cited study, explained
Plain-language walkthroughs of each reference, with direct PubMed links and dosing-literature context.