All categoriesCEREBROLYSINDAVUNETIDEDIHEXADSIPMELANOTAN-1MELANOTAN-2NOOPEPTOXYTOCINP21PINEALONPT-141SELANKSEMAX
Category
Cognitive & Neurotrophic
Peptides examined in neuroprotection, BDNF expression, and synaptic plasticity research.
Cognitive & Neurotrophic
Cerebrolysin
FPF-1070
- MW
- Peptide fraction < 10 kDa
- Half-life
- Variable by fraction
- Class
- Porcine brain-derived neuropeptide preparation
Cognitive & Neurotrophic
Davunetide
NAP · AL-108 · CP201
- MW
- 824.9 g/mol
- Half-life
- Short; intranasal delivery used in trials
- Class
- ADNP-derived microtubule-stabilising octapeptide
Cognitive & Neurotrophic
Dihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide · PNB-0408
- MW
- 473.6 g/mol
- Half-life
- Oral bioavailability reported; pharmacokinetics in humans not published
- Class
- Angiotensin IV analogue (oligopeptide)
Cognitive & Neurotrophic
DSIP
Delta Sleep-Inducing Peptide
- MW
- 848.8 g/mol
- Half-life
- ≈ 7–15 min (plasma)
- Class
- Nonapeptide neuromodulator
Cognitive & Neurotrophic
Melanotan-1
MT-1 · Afamelanotide
- MW
- 1646.8 g/mol
- Half-life
- ≈ 30 min (free); sustained-release implant approved
- Class
- α-MSH analogue (melanocortin agonist)
Cognitive & Neurotrophic
Melanotan-2
MT-2
- MW
- 1024.2 g/mol
- Half-life
- ≈ 33 min
- Class
- Cyclic α-MSH analogue (non-selective melanocortin agonist)
Cognitive & Neurotrophic
Noopept
GVS-111 · N-phenylacetyl-L-prolylglycine ethyl ester
- MW
- 318.4 g/mol
- Half-life
- ≈ 30–60 min (active metabolite cycloprolylglycine longer)
- Class
- Proline-containing dipeptide nootropic
Cognitive & Neurotrophic
Oxytocin
- MW
- 1007.2 g/mol
- Half-life
- ≈ 1–6 min (IV); ≈ 20 min (intranasal CNS effects)
- Class
- Nonapeptide neuropeptide / hormone
Cognitive & Neurotrophic
P21
P021 · Ciliary neurotrophic factor peptide mimetic
- MW
- ≈ 530 g/mol
- Half-life
- Not formally characterised in humans
- Class
- CNTF-derived neurogenic tetrapeptide
Cognitive & Neurotrophic
Pinealon
Glu-Asp-Arg · EDR peptide
- MW
- 418.4 g/mol
- Half-life
- Minutes
- Class
- Short bioregulator tripeptide (Khavinson peptide)
Cognitive & Neurotrophic
PT-141
Bremelanotide
- MW
- 1025.2 g/mol
- Half-life
- ≈ 2.7 h
- Class
- Melanocortin receptor agonist
Cognitive & Neurotrophic
Selank
- MW
- 751.9 g/mol
- Half-life
- Short (minutes, intranasal)
- Class
- Synthetic tuftsin analogue
Cognitive & Neurotrophic
Semax
- MW
- 813.9 g/mol
- Half-life
- Short (minutes, intranasal); CNS effects persist hours
- Class
- Synthetic ACTH(4-10) analogue