Pinealon
Also known as · Glu-Asp-Arg · EDR peptide
Overview
A three-amino-acid peptide bioregulator from the Russian Khavinson series, studied for neuroprotection under hypoxia and oxidative stress in cell and rodent models.
Research profile · for clinicians
Based on research: part of a family of short bioregulators proposed to interact directly with promoter regions of DNA. Data are largely Russian-language, preclinical, and mechanistically debated.
Mechanism of action
Proposed to penetrate the nucleus and bind specific DNA promoter sequences, modulating expression of genes governing antioxidant defence and neuronal survival.
Research record
- [01]Reduced markers of oxidative stress in hypoxia models.
- [02]No Western randomised human trials published.
Selected references
Peptide regulation of gene expression: Khavinson peptides
Bull. Exp. Biol. Med., 2011
Research deep dive
Every cited study, explained
Plain-language walkthroughs of each reference, with direct PubMed links and dosing-literature context.